Search results for "Cigarette smoking"

showing 10 items of 51 documents

Within subject variability of HDL-cholesterol in HIV-infected patients

2019

Background and objective: Within-subject variability of cardiovascular risk factors may influence the development of cardiovascular disease. We aimed to improve knowledge on HDL-cholesterol variability and its clinical significance in HIV-infected patients, a population at high risk of cardiovascular disease.Methods: This was a cohort study to quantify the variability of HDL-cholesterol between two consecutive visits and to determine factors associated with such variability, in a group of HIV-infected patients.Results: A total of 307 patients were included, mean ± standard deviation of their age was 45.1 ± 8.5 years, and 225 of them (73.3%) were male. The absolute difference (after squaring…

AdultBlood GlucoseMalemedicine.medical_specialtyAlcohol DrinkingWithin personPopulationBlood PressureHIV Infections030209 endocrinology & metabolismAbsolute difference030204 cardiovascular system & hematologyStandard deviationCigarette SmokingCohort Studies03 medical and health scienceschemistry.chemical_compoundSex Factors0302 clinical medicineHeart RateRisk FactorsInternal medicinemedicineHumansHiv infected patientsClinical significanceeducationeducation.field_of_studyCholesterolbusiness.industryCholesterol HDLAge FactorsGeneral MedicineMiddle AgedLipidsAnti-Retroviral AgentschemistryFemalelipids (amino acids peptides and proteins)businessCohort studyPostgraduate Medicine
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Effects of cigarette smoking or ingestion of nicotine on platelet 5-hydroxytryptamine (5-HT) levels in smokers and non-smokers.

1992

Platelets of healthy smokers and non-smokers were prepared and their content of 5-hydroxytryptamine was determined by HPLC with electrochemical detection. Platelet 5-HT levels in smokers (728 +/- 156 pmol per 10(8) platelets, mean +/- SEM, n = 9) were significantly higher than those in non-smokers (353 +/- 156 pmol per 10(8) platelets, n = 11). Smoking of a single cigarette caused a transient increase in platelet 5-HT levels by about 350% in non-smokers, but had no additional effect in smokers. Similarly, chewing of nicotine gum (4-8 mg nicotine) resulted in a transient increase in platelet 5-HT by about 100% in non-smokers, but not in smokers. In conclusion, smoking of cigarettes can cause…

AdultBlood Plateletsmedicine.medical_specialtyNicotineSerotoninAdministration OralReceptors NicotinicNicotine03 medical and health sciences0302 clinical medicineCigarette smokingInternal medicineDrug DiscoverymedicineEnterochromaffin CellsIngestionHumansPlateletReceptorGenetics (clinical)5-HT receptorbusiness.industrySmokingGeneral Medicinerespiratory tract diseases3. Good healthEndocrinologyNicotine gum030220 oncology & carcinogenesisReceptors Serotoninbehavior and behavior mechanismsMolecular MedicineSerotoninbusiness030217 neurology & neurosurgerymedicine.drugThe Clinical investigator
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Pain and swelling after periapical surgery related to oral hygiene and smoking.

2007

Objectives To evaluate pain and swelling during the first week after periapical surgery and its relation to patient age, gender, oral hygiene, and smoking. Study design One hundred two patients (31 men and 71 women) with a mean age of 40.2 years underwent periapical surgery. Age, gender, and oral hygiene and cigarette smoking before and during the postoperative course were noted. Pain and swelling scores were recorded on a descriptive 4-point scale at 2, 6, and 12 hours after surgery, and each day thereafter for 1 week. The data were statistically evaluated for significant differences. Results The highest intensity of pain occurred during the first 48 hours, and swelling peaked on the secon…

AdultMaleAdolescentOral Surgical ProceduresOral hygieneStatistics NonparametricSex FactorsCigarette smokingPatient ageEdemamedicineEdemaHumansIn patientProspective StudiesGeneral DentistryAgedAnalysis of VariancePain Postoperativebusiness.industryPeriapical DiseasesSmokingAge FactorsMean ageOral HygieneOtorhinolaryngologyAnesthesiaRetrograde ObturationSurgeryFemaleOral SurgerySwellingmedicine.symptombusinessPeriapical surgeryOral surgery, oral medicine, oral pathology, oral radiology, and endodontics
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Which group of smokers is more vulnerable to the economic crisis?

2016

Objectives: Studies investigating whether smoking increases or decreases during economic downturn provided contrasting results. For the first time, we used direct questions to analyse changes in smoking behaviour due to the 2008 financial crisis, comparing socio-economic characteristics of smokers who changed with those who kept their smoking intensity. Study Design: Cross-sectional survey. Methods: We used data from three annual surveys conducted in Italy in 2012-2014 on representative samples of te Italian general population aged >_15 years. Results: A total of 1919 current smokers were asked specific questions on the influence of the economic crisis that started in 2008 on their smoking …

AdultMaleAdolescentSmoking habitCross-sectional studymedia_common.quotation_subjectPopulation030508 substance abuseFamily incomeRecession03 medical and health sciencesYoung Adult0302 clinical medicineAge DistributionCigarette smokingMedicineHumans030212 general & internal medicineYoung adulteducationmedia_commonAgededucation.field_of_studybusiness.industrySmokingPublic Health Environmental and Occupational HealthGeneral MedicineMiddle AgedHealth SurveysCross-Sectional StudiesEconomic RecessionItalySocioeconomic FactorsFinancial crisisFemale0305 other medical sciencebusinessDemography
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Impulsiveness and venturesomeness in German smokers.

2011

Introduction Cigarette smoking is a behavior, which is influenced by genetic, demographic, and psychological factors. A large body of research has examined the association of cigarette smoking variables with individual differences in personality traits. The aim of the current study was to replicate the findings of higher self-reported impulsivity in smokers compared with never-smokers in a German sample using Eysenck´s construct of impulsivity. Furthermore, it was intended to further the knowledge about associations between different self-reported impulsivity components and different smoking variables. Methods We used the Impulsiveness-Venturesomeness-Empathy questionnaire (I7) to measure s…

AdultMaleImpulsivityGermanCigarette smokingGermanySurveys and QuestionnairesmedicineHumansBig Five personality traitsDemographySmokingPublic Health Environmental and Occupational HealthNovelty seekingTobacco Use DisorderMiddle Agedlanguage.human_languageSmoking epidemiologyLogistic ModelsImpulsive Behaviorbehavior and behavior mechanismslanguageExploratory BehaviorTemperament and Character InventorySmoking statusFemalemedicine.symptomPsychologyClinical psychologyNicotinetobacco research : official journal of the Society for Research on Nicotine and Tobacco
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Differences in psychomotor reaction time in male monozygotic twins discordant for lifetime cigarette smoking.

1996

The effects of long-term cigarette smoking on psychomotor reaction time were investigated among 8 pairs of monozygotic male twins highly discordant for lifetime smoking (means 32.4 versus 0.6 pack-years). The men had no diagnosed cardiovascular disease or other major diseases, musculoskeletal complaints, or vision problems that might interfere with reaction time testing. The twins had similar education, work, and exercise histories; alcohol and coffee consumption and exposure to solvents were examined as possible confounds. Direct comparison of cotwins also controlled for age, genetics, and possible early environmental factors. Simple and choice reaction time were measured in the dominant h…

AdultMaleNicotineChoice reaction timebusiness.industrySmokingExperimental and Cognitive PsychologyCoffee consumptionDiseaseTwins MonozygoticMiddle AgedSensory SystemsCohort StudiesCigarette smokingReaction TimeMedicineHumansPsychomotor reaction timebusinessPsychomotor PerformanceDemographyPerceptual and motor skills
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Airway epithelial dysfunction and mesenchymal transition in chronic obstructive pulmonary disease: Role of Oct-4

2021

Abstract The airway epithelium is a dynamic tissue that undergoes slow but constant renewal. Dysregulation of airway epithelial function related to cigarette smoke exposure plays an important role in the pathophysiology of COPD. Oct4 is a transcription factor responsible for maintaining cellular self-renewal and regeneration, and CD146 and CD105/Endoglin are adhesion molecules involved in cell proliferation, differentiation, epithelial-mesenchymal-transition and tissue remodeling. Bronchial biopsy specimens (BBs) were obtained from 7 healthy controls (HC) and 10 COPD and subjected to paraffin embedding; BBs from HC were also used for epithelial cell expansion and pHBEC/ALI (air-liquid inter…

AdultMalePathologymedicine.medical_specialtyEMT (epithelial-mesenchymal transition)Epithelial-Mesenchymal TransitionRespiratory SystemOct-4CD146 AntigenGeneral Biochemistry Genetics and Molecular BiologyCigarette SmokingPulmonary Disease Chronic ObstructiveAirway epithelium de-differentiationHumansMedicineGeneral Pharmacology Toxicology and PharmaceuticsAgedCOPDbusiness.industryCell adhesion moleculeMesenchymal stem cellEndoglinCell DifferentiationGeneral MedicineMiddle AgedEndoglinmedicine.diseaseCigarette smoke exposureEpitheliumrespiratory tract diseasesCD105medicine.anatomical_structureCD146Case-Control StudiesImmunohistochemistryRespiratory epitheliumCD146FemalebusinessOctamer Transcription Factor-3Life Sciences
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Cigarette Smoking and Drinking Water Source: Correlation with Clinical Features and Pathology of Superficial Bladder Carcinoma

2007

<i>Objective:</i> Water source and cigarette smoking are related to clinical characteristics and pathology of superficial transitional cell carcinoma of the bladder. <i>Methods:</i> Tumor number, dimension, G-grade, T-stage, recurrences, cigarette smoking and water supply were recorded in patients harboring Ta–T1 G1–3 transitional cell carcinoma of the bladder. <i>Results:</i> Of 577 patients, 61% had multiple and 36% recurrent tumors. Two hundred and forty-one patients (42%) were current smokers and 188 (33%) were former smokers. Bottled water was the only drinkable source for 249 (45%) patients, municipal water supply for 177 (32%), artesian wells for 3…

AdultMalePathologymedicine.medical_specialtyUrologyWater sourceRisk AssessmentCigarette smokingRecurrenceRisk FactorsWater SupplyOdds RatioCarcinomaHumansMedicineWater PollutantsAgedNeoplasm StagingAged 80 and overCarcinoma Transitional CellBladder cancerbusiness.industrySmokingdigestive oral and skin physiologyOdds ratioMiddle Agedmedicine.diseaseTransitional cell carcinomaItalyUrinary Bladder NeoplasmsMultivariate AnalysisFemaleNeoplasm stagingSuperficial Bladder CarcinomabusinessUrologia Internationalis
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Tobacco smoking and nicotine dependence in first episode and established psychosis

2019

Aim\ud People with psychotic disorders have increased premature mortality in comparison with the general population, with high rates of cigarette use a contributing factor. We aimed to describe the prevalence of cigarette use and nicotine dependence (ND) in first episode psychosis (FEP), and established psychosis; and to investigate associations between clinical symptoms and ND.\ud \ud Methodology\ud Smoking and clinical data were collected from two cohorts: 181 people with FEP recruited as part of the Physical Health and Substance Use Measures in First Onset Psychosis (PUMP) study and from 432 people with established psychosis recruited as part of the Improving\ud physical health and reduc…

AdultMalePsychosismedicine.medical_specialtyAdolescentmedia_common.quotation_subjectmedicine.medical_treatmentPopulationAddictionPhysical healthComorbiditySubstance useCigarette SmokingNicotineYoung AdultmedicineHumanseducationPsychiatryPsychoticGeneral PsychologyRandomized Controlled Trials as Topicmedia_commonFirst episodeeducation.field_of_studybusiness.industryAddictionSmokingTobacco Use DisorderGeneral Medicinemedicine.diseaseUnited KingdomPsychiatry and Mental healthPsychotic DisordersSchizophreniaCohortSchizophreniaSmoking cessationFemalebusinessmedicine.drug
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Cigarette smoking and risk of Hodgkin lymphoma and its subtypes: a pooled analysis from the International Lymphoma Epidemiology Consortium (InterLymp…

2013

Kamper-Jorgensen, M Rostgaard, K Glaser, S L Zahm, S H Cozen, W Smedby, K E Sanjose, S Chang, E T Zheng, T La Vecchia, C Serraino, D Monnereau, A Kane, E V Miligi, L Vineis, P Spinelli, J J McLaughlin, J R Pahwa, P Dosman, J A Vornanen, M Foretova, L Maynadie, M Staines, A Becker, N Nieters, A Brennan, P Boffetta, P Cocco, P Hjalgrim, H eng 5 ROI CA69269/CA/NCI NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't England 2013/06/22 06:00 Ann Oncol. 2013 Sep;24(9):2245-55. doi: 10.1093/annonc/mdt218. Epub 2013 Jun 19.; International audience; BACKGROUND: The etiology of Hodgkin lymphoma (HL) remains incompletely characterized. Studies of the association between smok…

AdultMaleRiskOncologyEpstein-Barr Virus InfectionsHerpesvirus 4 Humanmedicine.medical_specialtyAdolescentReviewscigarette smokingYoung AdultNodular sclerosisRisk FactorsInternal medicineEpidemiologycase–controlmedicineHumansEpstein–Barr viruindividual patient data meta-analysisYoung adultAgedAged 80 and overbusiness.industrySmokingConfoundingCase-control studyTobacco Use DisorderHematologyOdds ratioMiddle Agedmedicine.diseaseHodgkin DiseaseLymphomaSocial ClassOncologyCase-Control StudiesImmunologyEtiologyFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieepidemiologybusinessHodgkin lymphomaAnnals of Oncology
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